The Characteristic of the Gastric Secretion After Gastric Cryodenervation and Cryopreserved Placenta Extract Administration

Background. Peptic ulcer is a prevalent gastrointestinal tract disease worldwide. One of the treatment methods for indicated pathology trunk gastric cryodenervation (TGC), feature which preservation regenerative potential n. vagus. Cryopreserved placenta extract (CPE) caught our attention among modern means capable stimulating regeneration processes. Objective. We are aimed to characterize state secretion after TGC and application СPE. Methods. was performed by cryoinfusion on front back trunks abdominal part Gastric studied using H.A. Shay method. Results. On 30th day TGC, statistically significant (p < 0.001) decrease in total acidity juice 33.7% 0.01) level free were observed compared intact animals. Administration СPE resulted 24.2 % 48.7% parameters rats. This led "free/bound acidity" ratio indicator animals (1.4 ± 0.03 RU) higher than similar esomeprazole usage or TGC. Conclusions. contributed partial vagus, as an increase 104.1 4.7 RU